DISEASES

Disease-gene associations mined from literature

Literature associating MGEA5 and vesicoureteral reflux

MGEA5 [ENSP00000354850]

Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; Isoform 1: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity; Belongs to the glycosyl hydrolase 84 family.

Synonyms:  MGEA5,  MGEA5p,  hMGEA5,  B3KMK2,  H7C3X0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM