DISEASES

Disease-gene associations mined from literature

Literature associating MT-ND1 and Leber hereditary optic neuropathy and dystonia

MT-ND1 [ENSP00000354687]

Mitochondrially encoded NADH dehydrogenase 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity); NADH:ubiquinone oxidoreductase core subunits

Synonyms:  MT-ND1,  ND1,  A6ZHG8,  D2Y6X6,  D2Y6X8 ...

Linkouts:  STRING  Pharos  UniProt