DISEASES

Disease-gene associations mined from literature

Literature associating COMT and paranoid schizophrenia

COMT [ENSP00000354511]

Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Seven-beta-strand methyltransferase motif containing

Synonyms:  COMT,  COMT-001,  COMT-002,  COMT-003,  COMT-004 ...

Linkouts:  STRING  Pharos  UniProt  OMIM