DISEASES

Disease-gene associations mined from literature

Literature associating NTRK3 and fibrosarcoma

NTRK3 [ENSP00000354207]

Neurotrophic tyrosine kinase, receptor, type 3; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation; I-set domain containing

Synonyms:  NTRK3,  NTRK3p,  hNTRK3,  A9X3Y2,  B7Z7U4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM