Disease-gene associations mined from literature

Literature associating CASS4 and palmoplantar keratoderma and congenital alopecia 2

CASS4 [ENSP00000353462]

Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading; Belongs to the CAS family.

Synonyms:  CASS4,  CASS4p,  hCASS4,  CASS4-001,  CASS4-002 ...

Linkouts:  STRING  Pharos  UniProt