Literature associating MAX and malignant pheochromocytoma
Class D basic helix-loop-helix protein 4; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Synonyms: MAX, A0A024R682, G3V2N4, G3V2R5, G3V302 ...