Literature associating TPM1 and hypertrophic cardiomyopathy
TPM1 [ENSP00000351022]
Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells . Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction . Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Synonyms: TPM1, TPM1p, hTPM1, A0A024R5W6, A0A087WTJ7 ...