DISEASES

Disease-gene associations mined from literature

Literature associating APOA4 and chylomicron retention disease

APOA4 [ENSP00000350425]

Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons; Belongs to the apolipoprotein A1/A4/E family.

Synonyms:  APOA4,  APOA4p,  hAPOA4,  APOA4-001,  P06727 ...

Linkouts:  STRING  Pharos  UniProt  OMIM