DISEASES

Disease-gene associations mined from literature

Literature associating GRM7 and autosomal dominant nonsyndromic deafness 28

GRM7 [ENSP00000350348]

Glutamate receptor, metabotropic 7; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity; Glutamate metabotropic receptors

Synonyms:  GRM7,  GRM7p,  hGRM7,  LOC100996542,  C9JMT3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM