DISEASES

Disease-gene associations mined from literature

Literature associating MAGEA1 and synovial sarcoma

MAGEA1 [ENSP00000349085]

Melanoma antigen family A, 1 (directs expression of antigen MZ2-E); May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes; MAGE family

Synonyms:  MAGEA1,  MAGEA1p,  hMAGEA1,  A8IF97,  P43355 ...

Linkouts:  STRING  Pharos  UniProt  OMIM