Literature associating MAGEA1 and testicular cancer
Melanoma antigen family A, 1 (directs expression of antigen MZ2-E); May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes; MAGE family
Synonyms: MAGEA1, MAGEA1p, hMAGEA1, A8IF97, P43355 ...