Literature associating DYNC1H1 and Charcot-Marie-Tooth disease X-linked recessive 2
Dynein, cytoplasmic 1, heavy chain 1; Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression; Belongs to the dynein heavy chain family.
Synonyms: DYNC1H1, DYNC1H1p, hDYNC1H1, B4DSR6, DNCHC1 ...