DISEASES

Disease-gene associations mined from literature

Literature associating WDR45 and West syndrome

WDR45 [ENSP00000348848]

WD repeat domain phosphoinositide-interacting protein 4; Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation; Belongs to the WD repeat SVP1 family.

Synonyms:  WDR45,  WDR45p,  hWDR45,  A0A024QYW6,  A0A024QYX1 ...

Linkouts:  STRING  Pharos  UniProt