DISEASES

Disease-gene associations mined from literature

Literature associating ERCC5 and pellagra

ERCC5 [ENSP00000347978]

Xeroderma pigmentosum group G-complementing protein; Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too; Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.

Synonyms:  ERCC5,  ERCC5p,  hERCC5,  F2Z2A1,  P28715 ...

Linkouts:  STRING  Pharos  UniProt  OMIM