DISEASES

Disease-gene associations mined from literature

Literature associating LEPREL4 and membranous glomerulonephritis

LEPREL4 [ENSP00000347649]

Prolyl 3-hydroxylase family member 4; Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly; Belongs to the leprecan family.

Synonyms:  LEPREL4,  LEPREL4p,  hLEPREL4,  B4DVZ5,  K7EJ03 ...

Linkouts:  STRING  Pharos  UniProt