DISEASES

Disease-gene associations mined from literature

Literature associating LINGO1 and essential tremor

LINGO1 [ENSP00000347451]

Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity); I-set domain containing

Synonyms:  LINGO1,  LINGO1p,  hLINGO1,  H0YMX3,  H0YNK7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM