Literature associating C5AR1 and complement component 3 deficiency
C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production; CD molecules
Synonyms: C5AR1, C5AR1p, hC5AR1, P21730, C5AR ...