Disease-gene associations mined from literature

Literature associating C5AR1 and neutropenia

C5AR1 [ENSP00000347197]

C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production; CD molecules

Synonyms:  C5AR1,  C5AR1p,  hC5AR1,  P21730,  C5A ...

Linkouts:  STRING  Pharos  UniProt  OMIM