DISEASES

Disease-gene associations mined from literature

Literature associating PDE5A and premature ejaculation

PDE5A [ENSP00000347046]

cGMP-binding cGMP-specific phosphodiesterase; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'- GMP. Specifically regulates nitric-oxide-generated cGMP; Phosphodiesterases

Synonyms:  PDE5A,  PDE5Ap,  hPDE5A,  C9JGT3,  G5E9C5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM