DISEASES

Disease-gene associations mined from literature

Literature associating VPS72 and bone chondrosarcoma

VPS72 [ENSP00000346464]

Vacuolar protein sorting-associated protein 72 homolog; Deposition-and-exchange histone chaperone specific for H2AFZ, specifically chaperones H2AFZ and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP- dependent exchange of histone H2AFZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

Synonyms:  VPS72,  VPS72p,  hVPS72,  Q15906,  Q15906p ...

Linkouts:  STRING  Pharos  UniProt