DISEASES

Disease-gene associations mined from literature

Literature associating ANXA2 and acute promyelocytic leukemia

ANXA2 [ENSP00000346032]

Placental anticoagulant protein IV; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9; Belongs to the annexin family.

Synonyms:  ANXA2,  ANXA2p,  hANXA2,  A0A024R5Z7,  H0YKL9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM