Disease-gene associations mined from literature

Literature associating MAFF and fibrosarcoma

MAFF [ENSP00000345393]

V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F; Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response; Belongs to the bZIP family. Maf subfamily.

Synonyms:  MAFF,  B0QY70,  B0QY71,  Q9ULX9,  B0QY70p ...

Linkouts:  STRING  Pharos  UniProt  OMIM