DISEASES

Disease-gene associations mined from literature

Literature associating SPRY4 and hypogonadism

SPRY4 [ENSP00000344967]

Sprouty homolog 4 (Drosophila); Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.

Synonyms:  SPRY4,  SPRY4p,  hSPRY4,  D6RB56,  Q9C004 ...

Linkouts:  STRING  Pharos  UniProt  OMIM