Literature associating SPRY4 and hypogonadotropic hypogonadism
Sprouty homolog 4 (Drosophila); Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.
Synonyms: SPRY4, SPRY4p, hSPRY4, D6RB56, Q9C004 ...