Literature associating SLC24A2 and oculocutaneous albinism type V
Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2; Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+); Solute carriers
Synonyms: SLC24A2, SLC24A2p, hSLC24A2, Q9UI40, NCKX2 ...