DISEASES

Disease-gene associations mined from literature

Literature associating IKZF3 and B-cell adult acute lymphocytic leukemia

IKZF3 [ENSP00000344544]

IKAROS family zinc finger 3 (Aiolos); Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2- dependent manner; Belongs to the Ikaros C2H2-type zinc-finger protein family.

Synonyms:  IKZF3,  IKZF3p,  hIKZF3,  Q9UKT9,  Q9UKT9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM