Literature associating IKZF3 and B-cell adult acute lymphocytic leukemia
IKAROS family zinc finger 3 (Aiolos); Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2- dependent manner; Belongs to the Ikaros C2H2-type zinc-finger protein family.
Synonyms: IKZF3, IKZF3p, hIKZF3, Q9UKT9, Q9UKT9p ...