Disease-gene associations mined from literature

Literature associating ATF3 and bone carcinoma

ATF3 [ENSP00000344352]

Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters; Basic leucine zipper proteins

Synonyms:  ATF3,  ATF3p,  hATF3,  ATF3DELTAZIP2EXOND'DE'E,  P18847 ...

Linkouts:  STRING  Pharos  UniProt  OMIM