Disease-gene associations mined from literature

Literature associating GRM8 and retinitis pigmentosa 10

GRM8 [ENSP00000344173]

Glutamate receptor, metabotropic 8; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Synonyms:  GRM8,  GRM8p,  hGRM8,  C9J7I1,  E7ETK3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM