DISEASES

Disease-gene associations mined from literature

Literature associating IFNAR2 and hepatitis B

IFNAR2 [ENSP00000343957]

Interferon (alpha, beta and omega) receptor 2; Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.

Synonyms:  IFNAR2,  IFNAR2p,  hIFNAR2,  C9JCU0,  C9JM33 ...

Linkouts:  STRING  Pharos  UniProt  OMIM