Literature associating TPSAB1 and hereditary mixed polyposis syndrome 2
Tryptase alpha/beta 1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates; Belongs to the peptidase S1 family. Tryptase subfamily.
Synonyms: TPSAB1, TPSAB1p, hTPSAB1, J3QTS8, P20231 ...