Literature associating STAT5A and myeloid and lymphoid neoplasms associated with FGFR1 abnormalities
Signal transducer and activator of transcription 5A; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation; SH2 domain containing
Synonyms: STAT5A, STAT5Ap, hSTAT5A, C9JVV6, K7EIF9 ...