Literature associating NEO1 and cerebellar ataxia, mental retardation and dysequlibrium syndrome
Immunoglobulin superfamily DCC subclass member 2; Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response; Belongs to the immunoglobulin superfamily. DCC family.
Synonyms: NEO1, NEO1p, hNEO1, A0A024R610, NEO1-001 ...