Literature associating SMPD1 and acquired hyperkeratosis
SMPD1 [ENSP00000340409]
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide (PubMed:1840600, PubMed:18815062, PubMed:27659707, PubMed:25920558). Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. ECO:0000269|PubMed:18815062, ECO:0000269|PubMed:25920558, Isoform 3 lacks residues that bind the cofactor Zn(2+) and has no enzyme activity; Belongs to the acid sphingomyelinase family.
Synonyms: SMPD1, SMPD1p, hSMPD1, E9PL59, E9PPK6 ...