DISEASES

Disease-gene associations mined from literature

Literature associating BRAT1 and astereognosia

BRAT1 [ENSP00000339637]

BRCA1-associated protein required for ATM activation protein 1; Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Plays a role in regulating mitochondrial function and cell proliferation. Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors.

Synonyms:  BRAT1,  BRAT1p,  hBRAT1,  BRAT1-001,  BRAT1-002 ...

Linkouts:  STRING  Pharos  UniProt