DISEASES

Disease-gene associations mined from literature

Literature associating ARHGAP6 and microphthalmia

ARHGAP6 [ENSP00000338967]

Rho-type GTPase-activating protein RhoGAPX-1; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology.

Synonyms:  ARHGAP6,  ARHGAP6p,  hARHGAP6,  ARHGAP6-001,  ARHGAP6-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM