DISEASES

Disease-gene associations mined from literature

Literature associating SNCA and frontotemporal dementia

SNCA [ENSP00000338345]

Synuclein, alpha (non A4 component of amyloid precursor); May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation; Parkinson disease associated genes

Synonyms:  SNCA,  D6RA31,  E7EPV7,  F6L6N6,  H6UYS0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM