DISEASES

Disease-gene associations mined from literature

Literature associating MXD4 and progressive multifocal leukoencephalopathy

MXD4 [ENSP00000337889]

Max-interacting transcriptional repressor MAD4; Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity); Basic helix-loop-helix proteins

Synonyms:  MXD4,  MXD4p,  hMXD4,  D3DVQ5,  D6RGV1 ...

Linkouts:  STRING  Pharos  UniProt