DISEASES

Disease-gene associations mined from literature

Literature associating DCX and occult macular dystrophy

DCX [ENSP00000337697]

Neuronal migration protein doublecortin; Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration; Doublecortin superfamily

Synonyms:  A8K340,  B4DM53,  DCX-001,  DCX-002,  DCX-003 ...

Linkouts:  STRING  Pharos  UniProt  OMIM