DISEASES

Disease-gene associations mined from literature

Literature associating RNASEH2B and Chilblain lupus

RNASEH2B [ENSP00000337623]

Aicardi-Goutieres syndrome 2 protein; Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

Synonyms:  RNASEH2B,  Q5TBB1,  DLEU8,  Q5TBB1p,  hQ5TBB1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM