Literature associating SRA1 and X-linked cone-rod dystrophy 2
Steroid receptor RNA activator protein; Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis; Belongs to the SRA1 family.
Synonyms: SRA1, SRA1p, hSRA1, Q9HD15, PP7684 ...