DISEASES

Disease-gene associations mined from literature

Literature associating ZNF224 and nephroblastoma

ZNF224 [ENSP00000337368]

Bone marrow zinc finger 2; May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells; Belongs to the krueppel C2H2-type zinc-finger protein family.

Synonyms:  ZNF224,  ZNF224p,  hZNF224,  K7EJ30,  K7EL24 ...

Linkouts:  STRING  Pharos  UniProt