Literature associating FIP1L1 and eosinophilia-myalgia syndrome
Factor interacting with PAPOLA and CPSF1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.
Synonyms: FIP1L1, FIP1L1p, hFIP1L1, H0Y8P7, Q6UN15 ...