Disease-gene associations mined from literature

Literature associating GRK1 and retinitis pigmentosa 2

GRK1 [ENSP00000334876]

Rhodopsin kinase GRK1; Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade . This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination (By similarity). May play a role in the maintenance of the outer nuclear layer in the retina (By similarity).

Synonyms:  GRK1,  GRK1p,  hGRK1,  Q15835,  Q15835p ...

Linkouts:  STRING  Pharos  UniProt  OMIM