Literature associating GRK1 and Leber congenital amaurosis 10
G protein-coupled receptor kinase 1; Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Synonyms: GRK1, GRK1p, hGRK1, Q15835, Q71VB6 ...