DISEASES

Disease-gene associations mined from literature

Literature associating FOXE3 and Peters anomaly

FOXE3 [ENSP00000334472]

Forkhead-related transcription factor 8; Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye; Forkhead boxes

Synonyms:  FOXE3,  FOXE3p,  hFOXE3,  Q13461,  FKHL12 ...

Linkouts:  STRING  Pharos  UniProt  OMIM