DISEASES

Disease-gene associations mined from literature

Literature associating KDM4D and patulous eustachian tube

KDM4D [ENSP00000334181]

JmjC domain-containing histone demethylation protein 3D; Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate; Lysine demethylases

Synonyms:  KDM4D,  KDM4Dp,  hKDM4D,  Q6B0I6,  JHDM3D ...

Linkouts:  STRING  Pharos  UniProt  OMIM