DISEASES

Disease-gene associations mined from literature

Literature associating F3 and essential thrombocythemia

F3 [ENSP00000334145]

Coagulation factor III (thromboplastin, tissue factor); Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

Synonyms:  F3,  F3p,  hF3,  P13726,  Q86SE7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM