DISEASES

Disease-gene associations mined from literature

Literature associating C17orf70 and Fanconi anemia complementation group J

C17orf70 [ENSP00000333283]

Fanconi anemia core complex-associated protein 100; Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.

Synonyms:  C17orf70,  E7EVV8,  F5GZS4,  F5H095,  F5H5G6 ...

Linkouts:  STRING  Pharos  UniProt