DISEASES

Disease-gene associations mined from literature

Literature associating UBA7 and acute promyelocytic leukemia

UBA7 [ENSP00000333266]

Ubiquitin-like modifier activating enzyme 7; Activates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein; Ubiquitin like modifier activating enzymes

Synonyms:  UBA7,  MIR5193,  UBA7p,  hUBA7,  MIR5193p ...

Linkouts:  STRING  Pharos  UniProt  OMIM