Literature associating MARCHF11 and multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly
MARCHF11 [ENSP00000333181]
E3 ubiquitin-protein ligase MARCHF11; E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.
Synonyms: MARCHF11, A6NNE9, H0Y9K6, MARCH11, A6NNE9p ...