Literature associating MARCH11 and multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly
MARCH11 [ENSP00000333181]
Membrane-associated RING finger protein 11; E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids; Membrane associated ring-CH-type fingers
Synonyms: MARCH11, MARCH11p, hMARCH11, A6NNE9, A6NNE9p ...